Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRKAA2 All Species: 13.33
Human Site: S348 Identified Species: 24.44
UniProt: P54646 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54646 NP_006243.2 552 62320 S348 Y L A S S P P S G S F M D D S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001086410 550 62775 D350 Y L A T S P P D S F L D D H H
Dog Lupus familis XP_546691 722 81319 T518 Y L A S S P P T G S F M D D S
Cat Felis silvestris
Mouse Mus musculus Q8BRK8 552 61988 S348 Y L A S S P P S G S F M D D S
Rat Rattus norvegicus Q09137 552 62239 T348 Y L A S S P P T G S F M D D M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506315 519 59478 D319 Y L A T S P P D S F L D D H H
Chicken Gallus gallus Q9IA88 798 88848 N425 F P V D P N F N G L F R N R S
Frog Xenopus laevis NP_001088426 560 64038 D359 Y L A T S P P D S F M E D P P
Zebra Danio Brachydanio rerio Q6NSM8 1187 130949 A442 G E E P S P E A M A R Y L S M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623371 515 58559 G316 E V H S A L L G G D P H D Q L
Nematode Worm Caenorhab. elegans Q95ZQ4 626 70425 E416 E T A K L S I E E F Y Q V T P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38997 535 61163 R339 N H L I E S L R N R T Q N D G
Baker's Yeast Sacchar. cerevisiae P06782 633 72027 L406 N K S V S D E L D T F L S Q S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 76.4 73.8 N.A. 97.6 98.1 N.A. 71.1 27.3 75.3 22.3 N.A. N.A. 66.1 53.6 N.A.
Protein Similarity: 100 N.A. 86.7 75.2 N.A. 98.5 99 N.A. 81.1 42.6 85 32.6 N.A. N.A. 77.7 65.6 N.A.
P-Site Identity: 100 N.A. 46.6 93.3 N.A. 100 86.6 N.A. 46.6 20 46.6 13.3 N.A. N.A. 20 6.6 N.A.
P-Site Similarity: 100 N.A. 53.3 100 N.A. 100 93.3 N.A. 53.3 40 53.3 26.6 N.A. N.A. 33.3 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 44.9 33.1 N.A.
Protein Similarity: N.A. N.A. N.A. 62.3 50.2 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 62 0 8 0 0 8 0 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 8 0 24 8 8 0 16 62 39 0 % D
% Glu: 16 8 8 0 8 0 16 8 8 0 0 8 0 0 0 % E
% Phe: 8 0 0 0 0 0 8 0 0 31 47 0 0 0 0 % F
% Gly: 8 0 0 0 0 0 0 8 47 0 0 0 0 0 8 % G
% His: 0 8 8 0 0 0 0 0 0 0 0 8 0 16 16 % H
% Ile: 0 0 0 8 0 0 8 0 0 0 0 0 0 0 0 % I
% Lys: 0 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 54 8 0 8 8 16 8 0 8 16 8 8 0 8 % L
% Met: 0 0 0 0 0 0 0 0 8 0 8 31 0 0 16 % M
% Asn: 16 0 0 0 0 8 0 8 8 0 0 0 16 0 0 % N
% Pro: 0 8 0 8 8 62 54 0 0 0 8 0 0 8 16 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 16 0 16 0 % Q
% Arg: 0 0 0 0 0 0 0 8 0 8 8 8 0 8 0 % R
% Ser: 0 0 8 39 70 16 0 16 24 31 0 0 8 8 39 % S
% Thr: 0 8 0 24 0 0 0 16 0 8 8 0 0 8 0 % T
% Val: 0 8 8 8 0 0 0 0 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 54 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _